[enchirito]

If it was me, I’d leave extra early like at 3:00AM which gives you a super easy drive through LA / Orange County and also skims through the worst of the San Diego southbound commuter traffic with the goal of crossing the border by 6:00 or 6:30AM at the latest. From there it’s easy to reach Guerrero Negro before sunset. Go to bed early that night to recoup and that will put you in San Juanico by the following afternoon.